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The aminopeptidase ERAAP shapes the peptide repertoire displayed by major histocompatibility complex class I molecules

✍ Scribed by Hammer, Gianna Elena; Gonzalez, Federico; Champsaur, Marine; Cado, Dragana; Shastri, Nilabh


Book ID
109923194
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
516 KB
Volume
7
Category
Article
ISSN
1529-2908

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Regulation of peptide presentation by ma
✍ Alexei von Delwig; Julie A. Musson; Norman McKie; Joe Gray; John H. Robinson πŸ“‚ Article πŸ“… 2003 πŸ› John Wiley and Sons 🌐 English βš– 283 KB

We studied major histocompatibility complex class II-dependent presentation of two T cell epitopes delivered as synthetic peptides by fixed macrophages. Treatment of bone marrow macrophages with inhibitors of proteinases of the metallo-, aspartic and serine proteinase families enhanced presentation