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The alliance of sphingosine-1-phosphate and its receptors in immunity

✍ Scribed by Rivera, Juan; Proia, Richard L.; Olivera, Ana

Book ID: 109955964
Publisher: Nature Publishing Group
Year: 2008
Tongue: English
Weight: 864 KB
Volume: 8
Category: Article
ISSN: 1474-1741
DOI: 10.1038/nri2400

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## Abstract The lysophospholipid growth factors sphingosine 1‐phosphate (S1P) and lysophosphatidic acid (LPA) are generated by many cells involved in immunity, including macrophages, dendritic cells, mast cells, and platelets, with resultant lymph and plasma concentrations of 0.1–1 μM. All immune c