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The Activity of SV40 Promoter Can Be Inhibited by Overexpression of Heme Oxygenase-1 in Tumor Cells

✍ Scribed by Qingjun Liu, Yujing Yin, Bo Wang, Hong Zhou


Book ID
120897732
Publisher
Springer-Verlag
Year
2012
Tongue
English
Weight
429 KB
Volume
65
Category
Article
ISSN
1085-9195

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## Abstract Extracellular acidosis (EA) regulates Heme Oxygenase‐1 (HO‐1) expression in vascular smooth muscle cells via transcriptional and posttranscriptional mechanisms but the signaling pathways involved are not known. We examined the role of Mitogen‐Activated Protein Kinase (MAPK) pathways in