Exposure of the basal-lateral surfaces of MDCK epithelia, mounted in Ussing chambers, to medium made hyperosmotic by the non-electrolyte mannitol, resulted in a marked inhibition of the adrenalinestimulated inward short-circuit current (C1-secretion). This inhibition was unaccompanied by a reversal
The action of ouabain upon chloride secretion in cultured MDCK epithelium
โ Scribed by N.L Simmons
- Book ID
- 115725187
- Publisher
- Elsevier Science
- Year
- 1981
- Tongue
- English
- Weight
- 630 KB
- Volume
- 646
- Category
- Article
- ISSN
- 0005-2736
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Regulatory volume decrease after exposure to hypo-osmotic media in MDCK epithelial cells results from activation of both K+ and Cl- conductances. Swelling-stimulated 86Rb(K) losses were observed only across the basal-lateral membrane and were relatively insensitive to 10 mM Ba2+. The effect of hypo-
SUBSTANCE named kinetin' has been iso-A lated and described as "a physiologically highly active chemical" capable of stimulating cell division. This was demonstrated in tissue cultures o E tobacco "wound" callus tissue. Miller, Skoog, Von Saltza, and Strong2 found that concentrations of kinetin as l