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The absolute configuration of the four stereoisomers of trans-anethole diol (1-(4′-methoxyphenyl)-1,2-propanediol), a metabolite of anethole in the rat

✍ Scribed by Takashi Ishida; Stephen V.J. Bounds; John Caldwell; Alex Drake; Mitsuhiro Takeshita


Book ID
103977679
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
288 KB
Volume
7
Category
Article
ISSN
0957-4166

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✍ H. Yagi; D.R. Thakker; Y. Ittah; M. Croisy-Delcey; D.M. Jerina 📂 Article 📅 1983 🏛 Elsevier Science 🌐 French ⚖ 278 KB

The (+)-and (-)-trans-3,4-dihydroxy-3,4-dihydrobenzo[c]phenanthrenes have been resolved and assigned absolute configuration by independent nmr and CD methods. Each was converted to its pair of diastereomeric bay-region 3,4-diol-1,2-epoxides in which the benzylic 4-hydroxyl group is either cis or tra