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The 5HT3antagonist GR38032F is highly toxic in DBA/2 mice

โœ Scribed by C. A. Hendrie

Book ID
105509948
Publisher
Springer
Year
1990
Tongue
English
Weight
246 KB
Volume
101
Category
Article
ISSN
0033-3158

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GR38032F, a 5HT3receptor antagonist, in
GR38032F, a 5HT3receptor antagonist, in the prophylaxis of acute cisplatin-induced nausea and vomiting
โœ Michel Marty; Jean P. Droz; Pierre Pouillart; Bernard Paule; Nils Brion; Jacques ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› Springer ๐ŸŒ English โš– 330 KB

A total of 28 patients receiving cancer chemotherapy with cisplatin-containing regimens (70-120 mg/ m 2) participated in an evaluation of the efficacy and safety of GR38032F for the prevention of acute nausea and vomiting. GR38032F, a 5HT3 receptor antagonist, was given 30 min prior to cisplatin as