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The efficacy of GR38032F, an Antagonist of 5-hydroxytryptamine-3 (5-HT3) in the prophylaxis of cisplatin (CDDP)-induced nausea and vomiting

โœ Scribed by De Haan, Louis D.; De Mulder, Pieter H.M.; Beex, Louk V.A.M.; Debruyne, Frans M.J.; Challoner, Teresa; De Pauw, Ben E.

Book ID
122675885
Publisher
Elsevier Science
Year
1988
Weight
132 KB
Volume
24
Category
Article
ISSN
0277-5379

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GR38032F, a 5HT3receptor antagonist, in
GR38032F, a 5HT3receptor antagonist, in the prophylaxis of acute cisplatin-induced nausea and vomiting
โœ Michel Marty; Jean P. Droz; Pierre Pouillart; Bernard Paule; Nils Brion; Jacques ๐Ÿ“‚ Article ๐Ÿ“… 1989 ๐Ÿ› Springer ๐ŸŒ English โš– 330 KB

A total of 28 patients receiving cancer chemotherapy with cisplatin-containing regimens (70-120 mg/ m 2) participated in an evaluation of the efficacy and safety of GR38032F for the prevention of acute nausea and vomiting. GR38032F, a 5HT3 receptor antagonist, was given 30 min prior to cisplatin as