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The 5′ Regulatory Region of the Human Fetal Globin Genes is a Gene Conversion Hotspot

✍ Scribed by Kalamaras, Angelos; Chassanidis, Christos; Samara, Maria; Chiotoglou, Ioanna; Vamvakopoulos, Nikolaos K.; Papadakis, Manoussos N.; Kollia*, Panagoula; Patrinos, George P.


Book ID
120188509
Publisher
Informa plc
Year
2008
Tongue
English
Weight
543 KB
Volume
32
Category
Article
ISSN
0363-0269

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Extent and high frequency of a short con
✍ J. Starck; R. Bouhass; F. Morlé; J. Godet 📂 Article 📅 1990 🏛 Springer 🌐 English ⚖ 806 KB

Southern blotting and DNA sequencing after polymerase chain reaction (PCR) amplification provide evidence for the frequent occurrence (in 7 out of 24 chromosomes) of a short conversion G gamma----A gamma in the 3' end of the human fetal A gamma globin gene. This short conversion is characterized by