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The 3′-untranslated sequence of human skeletal muscle α-actin mRNA

✍ Scribed by G. Gillespie; J. Lloyd; D. Hopkinson; Y. Edwards


Book ID
104954376
Publisher
Springer Netherlands
Year
1984
Tongue
English
Weight
852 KB
Volume
5
Category
Article
ISSN
0142-4319

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The ACTA1 gene encodes skeletal muscle a-actin, which is the predominant actin isoform in the sarcomeric thin filaments of adult skeletal muscle, and essential, along with myosin, for muscle contraction. ACTA1 disease-causing mutations were first described in 1999, when a total of 15 mutations were