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Nucleotide sequence of the rat skeletal muscle actin gene

โœ Scribed by Zakut, R.; Shani, M.; Givol, D.; Neuman, S.; Yaffe, D.; Nudel, U.


Book ID
109727374
Publisher
Nature Publishing Group
Year
1982
Tongue
English
Weight
373 KB
Volume
298
Category
Article
ISSN
0028-0836

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The ACTA1 gene encodes skeletal muscle a-actin, which is the predominant actin isoform in the sarcomeric thin filaments of adult skeletal muscle, and essential, along with myosin, for muscle contraction. ACTA1 disease-causing mutations were first described in 1999, when a total of 15 mutations were