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Activation of the skeletal α-actin promoter during muscle regeneration

✍ Scribed by Daniel R. Marsh; James A. Carson; Lynn N. Stewart; Frank W. Booth


Book ID
110225192
Publisher
Springer Netherlands
Year
1998
Tongue
English
Weight
151 KB
Volume
19
Category
Article
ISSN
0142-4319

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The ACTA1 gene encodes skeletal muscle a-actin, which is the predominant actin isoform in the sarcomeric thin filaments of adult skeletal muscle, and essential, along with myosin, for muscle contraction. ACTA1 disease-causing mutations were first described in 1999, when a total of 15 mutations were