𝔖 Bobbio Scriptorium
✦   LIBER   ✦

The 1α,25-dihydroxy Vitamin D3 receptor preferentially recruits the coactivator SRC-1 during up-regulation of the osteocalcin gene

✍ Scribed by Loreto Carvallo; Berta Henriquez; Juan Olate; Andre J. van Wijnen; Jane B. Lian; Gary S. Stein; Sergio Onate; Janet L. Stein; Martin Montecino

Book ID
116697926
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
276 KB
Volume
103
Category
Article
ISSN
0960-0760

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

1α,25-dihydroxy vitamin D3-enhanced expr
1α,25-dihydroxy vitamin D3-enhanced expression of the osteocalcin gene involves increased promoter occupancy of basal transcription regulators and gradual recruitment of the 1α,25-dihydroxy vitamin D3 receptor-SRC-1 coactivator complex
✍ Loreto Carvallo; Berta Henríquez; Roberto Paredes; Juan Olate; Sergio Onate; And 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 289 KB

## Abstract Binding of 1α,25‐dihydroxy vitamin D~3~ to the C‐terminal ligand‐binding domain (LBD) of its receptor (VDR) induces a conformational change that enables interaction of VDR with transcriptional coactivators such as members of the p160/SRC family or the DRIP (vitamin D receptor‐interactin

The classic receptor for 1α,25-dihydroxy
The classic receptor for 1α,25-dihydroxy vitamin D3 is required for non-genomic actions of 1α,25-dihydroxy vitamin D3 in osteosarcoma cells
✍ Soraya Bravo; Roberto Paredes; Pamela Izaurieta; Jane B. Lian; Janet L. Stein; G 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 110 KB

1a,25-dihydroxy vitamin D3 has a major role in the regulation of the bone metabolism as it promotes the expression of key bone-related proteins in osteoblastic cells. In recent years it has become increasingly evident that in addition to its well-established genomic actions, 1a,25-dihydroxy vitamin

1α,25-dihydroxy vitamin D3 induces nucle
1α,25-dihydroxy vitamin D3 induces nuclear matrix association of the 1α,25-dihydroxy vitamin D3 receptor in osteoblasts independently of its ability to bind DNA
✍ Gloria Arriagada; Roberto Paredes; Andre J. van Wijnen; Jane B. Lian; Brigitte v 📂 Article 📅 2010 🏛 John Wiley and Sons 🌐 English ⚖ 635 KB

## Abstract 1α,25‐dihydroxy vitamin D~3~ (vitamin D~3~) has an important role during osteoblast differentiation as it directly modulates the expression of key bone‐related genes. Vitamin D~3~ binds to the vitamin D~3~ receptor (VDR), a member of the superfamily of nuclear receptors, which in turn i