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TGFβ2-mediated production of hyaluronan is important for the induction of epicardial cell differentiation and invasion

✍ Scribed by Evisabel A. Craig; Anita F. Austin; Richard R. Vaillancourt; Joey V. Barnett; Todd D. Camenisch


Book ID
113956042
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
996 KB
Volume
316
Category
Article
ISSN
0014-4827

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✍ Volker Ellenrieder; Sandra F. Hendler; Claudia Ruhland; Wolfgang Boeck; Guido Ad 📂 Article 📅 2001 🏛 John Wiley and Sons 🌐 French ⚖ 216 KB

TGF-beta strongly promotes local tumor progression in advanced epithelial tumors, though the underlying mechanisms are poorly understood. In the present study, we demonstrate the potential of TGF-beta to increase the invasiveness of the pancreatic cancer cell lines PANC-1 and IMIM-PC1. TGF-beta-indu