𝔖 Bobbio Scriptorium
✦   LIBER   ✦

TGFβ1/Smad3 counteracts BRCA1-dependent repair of DNA damage

✍ Scribed by Dubrovska, Anna; Kanamoto, Takashi; Lomnytska, Marta; Heldin, Carl-Henrik; Volodko, Natalya; Souchelnytskyi, Serhiy


Book ID
110069501
Publisher
Nature Publishing Group
Year
2005
Tongue
English
Weight
383 KB
Volume
24
Category
Article
ISSN
0950-9232

No coin nor oath required. For personal study only.


📜 SIMILAR VOLUMES


TGF-β1-induced Smad 3 binding to the Sma
✍ Kenneth R. Cutroneo; Sem H. Phan 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 175 KB

## Abstract Bleomycin produces its fibrogenic effect, at least in part, by TGF‐β1 secretion. Treatment of IMR‐90 human embryonic lung fibroblasts with bleomycin at 0.5 μg/ml results in a 1.6‐fold increase of TGF‐β1 as determined by a specific ELISA assay for TGF‐β1 after acidification of the condit

Identification of novel Smad2 and Smad3
✍ Kimberly A. Brown; Amy-Joan L. Ham; Cara N. Clark; Nahum Meller; Brian K. Law; A 📂 Article 📅 2008 🏛 John Wiley and Sons 🌐 English ⚖ 577 KB

## Abstract Transforming growth factor‐beta 1 (TGF‐β1) is an important growth inhibitor of epithelial cells and insensitivity to this cytokine results in uncontrolled cell proliferation and can contribute to tumorigenesis. TGF‐β1 signals through the TGF‐β type I and type II receptors, and activates