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TGF-β inhibits growth and induces apoptosis in leukemic B cell precursors

✍ Scribed by Buske, C; Becker, D; Feuring-Buske, M; Hannig, H; Wulf, G; Schäfer, C; Hiddemann, W; Wörmann, B

Book ID
110053444
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
186 KB
Volume
11
Category
Article
ISSN
0887-6924

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✍ K. Komatsu; H. Nakamura; H. Akedo 📂 Article 📅 1993 🏛 Elsevier Science 🌐 English ⚖ 362 KB

## Abstract The production of the leukemic cell‐growth‐promoting factor (LGF) in TGF‐β1‐treated fibroblast cells was studied. BALB/c3T3 mouse fibroblast(3T3) cells cultured in Eagle's medium containing a low concentration of TGF‐β1 (0.04‐1 ng/ml) secreted 3‐5 times more LGF than the cells cultured