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Smad7 induces tumorigenicity by blocking TGF-β-induced growth inhibition and apoptosis

✍ Scribed by Sunil K. Halder; R. Daniel Beauchamp; Pran K. Datta


Book ID
118506113
Publisher
Elsevier Science
Year
2005
Tongue
English
Weight
882 KB
Volume
307
Category
Article
ISSN
0014-4827

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## Abstract Transforming growth factor‐β (TGF‐β) is a multifunctional growth factor, affecting cell proliferation, apoptosis, and extracellular matrix homeostasis. It also plays critical roles in mammary gland development, one of which involves inhibition of the expression of milk proteins, such as