Transcriptional regulation of Smad2 is r
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Steven A. Johnsen; Malayannan Subramaniam; Takenobu Katagiri; Ralf Janknecht; Th
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Article
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2002
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John Wiley and Sons
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English
⚖ 178 KB
TGFbeta inducible early gene (TIEG) is a novel Krüppel-like transcriptional repressor that was recently shown to increase the activity of the TGFbeta/Smad signal transduction pathway by relieving negative feedback through repression of the inhibitory Smad7. Interestingly, while Smad7 is required for