✦ LIBER ✦

HDAC-mediated control of ERK- and PI3K-dependent TGF-β-induced extracellular matrix-regulating genes

✍ Scribed by Matt J. Barter; Leon Pybus; Gary J. Litherland; Andrew D. Rowan; Ian M. Clark; Dylan R. Edwards; Tim E. Cawston; David A. Young

Book ID: 116729931
Publisher: Elsevier Science
Year: 2010
Tongue: English
Weight: 803 KB
Volume: 29
Category: Article
ISSN: 0945-053X
DOI: 10.1016/j.matbio.2010.05.002

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

PI3K/Akt pathway mediates high glucose-i

PI3K/Akt pathway mediates high glucose-induced lipogenesis and extracellular matrix accumulation in HKC cells through regulation of SREBP-1 and TGF-β1

✍ Jun Hao; Shuxia Liu; Song Zhao; Qingjuan Liu; Xin Lv; Huan Chen; Yunyi Niu; Huij 📂 Article 📅 2011 🏛 Springer 🌐 English ⚖ 524 KB

MiR-29 mediates TGFβ1-induced extracellu

MiR-29 mediates TGFβ1-induced extracellular matrix synthesis through activation of PI3K-AKT pathway in human lung fibroblasts

✍ Yang, Tao; Liang, Ying; Lin, Qinlu; Liu, Junwen; Luo, Feijun; Li, Xinhua; Zhou, 📂 Article 📅 2013 🏛 John Wiley and Sons 🌐 English ⚖ 908 KB

TL1A induces the expression of TGF-β-ind

TL1A induces the expression of TGF-β-inducible gene h3 (βig-h3) through PKC, PI3K, and ERK in THP-1 cells

✍ Seung-Hee Lee; Eun-Ju Kim; Kyoungho Suk; In-San Kim; Won-Ha Lee 📂 Article 📅 2010 🏛 Elsevier Science 🌐 English ⚖ 584 KB

TGF-β-induced expression of tissue inhib

TGF-β-induced expression of tissue inhibitor of metalloproteinases-3 gene in chondrocytes is mediated by extracellular signal-regulated kinase pathway and Sp1 transcription factor

✍ Hamid Yaqoob Qureshi; Judith Sylvester; Mohammed El Mabrouk; Muhammad Zafarullah 📂 Article 📅 2005 🏛 John Wiley and Sons 🌐 English ⚖ 422 KB

## Abstract Transforming growth factor (TGF‐β1) is a potent inducer of chondrogenesis and stimulant of cartilage extracellular matrix (ECM) synthesis. Tissue inhibitor of metalloproteinases‐3 (TIMP‐3) is located in ECM and is the major inhibitor of matrix metalloproteinases (MMPs) and aggrecanase,