Tetrahydropyran as an efficient alcohol protecting group for the synthesis of penems: synthesis of Sch 34343
โ Scribed by Gala, D.; Steinman, M.; Jaret, R. S.
- Book ID
- 127054155
- Publisher
- American Chemical Society
- Year
- 1986
- Tongue
- English
- Weight
- 435 KB
- Volume
- 51
- Category
- Article
- ISSN
- 0022-3263
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๐ SIMILAR VOLUMES
5-Chloro-8-quinolyl group is found to be very suitable for the protecting group on phosphates in the internucleotidic bonds.
Enzymatic protecting group techniques are used for the selective synthesis of acid-and base labile multifunctional nucleopeptides under mild conditions.
In the course of studies directed towards the total synthesis of trichodermin 1 and trichothecolone 2 we required the a,B-unsaturated Ketones 1 and Q,and the cis-ketol 1 2. We wish to report, first,the preparation of the diketoethers 5 and 1 and their cyclization to give 2 and 4\_, respectively. Bot