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Terminal Deoxyribonucleotidyl Transferase in Human Leukemia

✍ Scribed by Mary Sue Coleman, John J. Hutton, Philip De Simone and F. J. Bollum

Book ID
123652933
Publisher
National Academy of Sciences
Year
1974
Tongue
English
Weight
981 KB
Volume
71
Category
Article
ISSN
0027-8424

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✍ Kristijan Ramadan; Igor V Shevelev; Giovanni Maga; Ulrich HΓΌbscher πŸ“‚ Article πŸ“… 2004 πŸ› Elsevier Science 🌐 English βš– 825 KB

DNA polymerases (pols) catalyse the synthesis of DNA. This reaction requires a primer-template DNA in order to grow from the 3 0 OH end of the primer along the template. On the other hand terminal deoxyribonucleotidyl transferase (TdT) catalyses the addition of nucleotides at the 3 0 OH end of a DNA