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Terminal deoxynucleotidyl transferase activity in childhood leukemia

✍ Scribed by Naomi Winick; Peter G. Steinherz; Denis R. Miller


Publisher
John Wiley and Sons
Year
1985
Tongue
English
Weight
387 KB
Volume
55
Category
Article
ISSN
0008-543X

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πŸ“œ SIMILAR VOLUMES


Simultaneous evaluation for terminal deo
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## Abstract A technique for dual staining of cells using terminal deoxynucleotidyl transferase (TdT) and myeloperoxidase (MPO) is described. The technique has been applied to cells of two patients. One patient had chronic myelomonocytic leukemia evolving into acute myelomonocytic leukemia. The othe

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## Abstract A 165,000g pellet fraction, isolated from lysed rooster spermatozoa, was shown to contain a deoxynucleotide polymerizing activity which banded in sucrose at a buoyant density of 1.15gm/ml. The solubilized enzyme, partially purified by gel filtration, was estimated to have a molecular we

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## Abstract Specificity of TdT^5^ as a marker for ALL was evaluated by determining its activity in cells from normal control subjects and from 35 pediatric patients with ALL, AML, Hodgkin's disease and disseminated Burkitt's lymphoma. We evaluated the DNA polymerase activity, cell surface pheno‐typ