Surface phenotyping by flow cytometry and cytochemical study were used to identify 15 adult patients with acute leukemia displaying ambiguous phenotypes. Differences were found in the blast cell karyotype and immunoglobulin gene rearrangements of terminal deoxynucleotidyl transferase (TdT)-positive
Terminal deoxynucleotidyl transferase-positive acute leukemias evolving from a myelodysplastic syndrome
β Scribed by E. Brusamolino; P. Isernia; E. P. Alessandrino; A. I. Scovassi; U. Bertazzoni; C. Bernasconi
- Publisher
- John Wiley and Sons
- Year
- 1985
- Tongue
- English
- Weight
- 224 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0361-8609
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In this report, we describe a case of acute leukemia possessing a unique immunophenotype. Leukemic cells isolated from peripheral blood were analyzed by automated fluorescence-activated flow cytometry. They demonstrated the following antigen pattern: CD7 +, CD38 +, transferrin receptor + , HLA-DR +