Lack of antileukemic activity of rapamycin in elderly patients with acute myeloid leukemia evolving from a myelodysplastic syndrome
โ Scribed by Fernando Callera; Carlos O. Lopes; Evandro S. Rosa; Carla C. Mulin
- Publisher
- Elsevier Science
- Year
- 2008
- Tongue
- English
- Weight
- 67 KB
- Volume
- 32
- Category
- Article
- ISSN
- 0145-2126
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๐ SIMILAR VOLUMES
## Abstract ## BACKGROUND Levels of the soluble form of CD86 (sCD86) are elevated in a proportion of patients with leukemia. Although it is a potential modulator of antitumor responses, the significance of sCD86 in patients with hematologic malignancies is unknown. ## METHODS The authors evaluat
## Abstract ## BACKGROUND. The poor prognosis for elderly patients with acute myeloid leukemia (AML) raises questions regarding the benefit of treating them with intensive chemotherapy. The impact of initial characteristics on prognosis has been addressed previously in elderly patients; however, v