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Therapy for elderly patients with acute myeloid leukemia : A problem in search of solutions

โœ Scribed by Hagop M. Kantarjian


Publisher
John Wiley and Sons
Year
2007
Tongue
English
Weight
71 KB
Volume
109
Category
Article
ISSN
0008-543X

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Eighteen patients aged 60-84 years with acute myeloid leukemia were treated with lowdose combination chemotherapy comprising cytarabine, etoposide, and mitozantrone or 6-thioguanine; seven of these patients had a pre-existing myelodysplastic syndrome. Nine patients achieved a complete remission, and

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## Abstract ## BACKGROUND. The poor prognosis for elderly patients with acute myeloid leukemia (AML) raises questions regarding the benefit of treating them with intensive chemotherapy. The impact of initial characteristics on prognosis has been addressed previously in elderly patients; however, v