De Novo DNA Synthesis by Human DNA Polym
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Kristijan Ramadan; Igor V Shevelev; Giovanni Maga; Ulrich Hübscher
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Article
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2004
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Elsevier Science
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English
⚖ 825 KB
DNA polymerases (pols) catalyse the synthesis of DNA. This reaction requires a primer-template DNA in order to grow from the 3 0 OH end of the primer along the template. On the other hand terminal deoxyribonucleotidyl transferase (TdT) catalyses the addition of nucleotides at the 3 0 OH end of a DNA