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De Novo DNA Synthesis by Human DNA Polymerase λ, DNA Polymerase μ and Terminal Deoxyribonucleotidyl Transferase

✍ Scribed by Kristijan Ramadan; Igor V Shevelev; Giovanni Maga; Ulrich Hübscher


Book ID
116661281
Publisher
Elsevier Science
Year
2004
Tongue
English
Weight
825 KB
Volume
339
Category
Article
ISSN
0022-2836

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De Novo DNA Synthesis by Human DNA Polym
✍ Kristijan Ramadan; Igor V Shevelev; Giovanni Maga; Ulrich Hübscher 📂 Article 📅 2004 🏛 Elsevier Science 🌐 English ⚖ 825 KB

DNA polymerases (pols) catalyse the synthesis of DNA. This reaction requires a primer-template DNA in order to grow from the 3 0 OH end of the primer along the template. On the other hand terminal deoxyribonucleotidyl transferase (TdT) catalyses the addition of nucleotides at the 3 0 OH end of a DNA