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Efficiency and fidelity of human DNA polymerases λ and β during gap-filling DNA synthesis

✍ Scribed by Jessica A. Brown; Lindsey R. Pack; Laura E. Sanman; Zucai Suo


Book ID
113568252
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
895 KB
Volume
10
Category
Article
ISSN
1568-7864

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DNA polymerase lambda (Pol lambda) is a novel enzyme of the family X of DNA polymerases. Pol lambda has some properties in common with DNA polymerase beta (Pol beta). The substrate properties of Pol lambda were compared to Pol beta using DNAs mimicking short-patch (SP) and long-patch (LP) base excis