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DNA binding properties of human DNA polymerase η: implications for fidelity and polymerase switching of translesion synthesis

✍ Scribed by Rika Kusumoto; Chikahide Masutani; Shizu Shimmyo; Shigenori Iwai; Fumio Hanaoka

Book ID
108731718
Publisher
John Wiley and Sons
Year
2004
Tongue
English
Weight
338 KB
Volume
9
Category
Article
ISSN
1356-9597

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New triphosphate derivatives of carbocyclic nucleoside analogues have been synthesized and shown to be potent substrates for terminal deoxynucleotidyltransferase and/or HIV reverse transcriptase; the compounds are stable to dephosphorylation with human placental alkaline phosphatase.