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Substrates for Investigation of DNA Polymerase Function: Synthesis and Properties of 4′-C-Alkylated Oligonucleotides

✍ Scribed by Ilka Detmer; Daniel Summerer; Andreas Marx


Publisher
John Wiley and Sons
Year
2003
Tongue
English
Weight
181 KB
Volume
2003
Category
Article
ISSN
1434-193X

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Cover Picture: Substrates for Investigat
✍ Ilka Detmer; Daniel Summerer; Andreas Marx 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 75 KB 👁 2 views

## Abstract **The cover picture shows** the design and structures of 4′‐__C__‐alkylated thymidines. These modified nucleosides were synthesized and subsequently incorporated into oligonucleotides to probe inherent properties of the DNA double helix (left‐hand) side) and DNA polymerases in their int