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4′C-Modified Nucleotides as Chemical Tools for Investigation and Modulation of DNA Polymerase Function

✍ Scribed by Daniel Summerer; Andreas Marx


Publisher
John Wiley and Sons
Year
2004
Weight
52 KB
Volume
35
Category
Article
ISSN
0931-7597

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✦ Synopsis


Abstract

For Abstract see ChemInform Abstract in Full Text.


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Cover Picture: Substrates for Investigat
✍ Ilka Detmer; Daniel Summerer; Andreas Marx 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 75 KB 👁 2 views

## Abstract **The cover picture shows** the design and structures of 4′‐__C__‐alkylated thymidines. These modified nucleosides were synthesized and subsequently incorporated into oligonucleotides to probe inherent properties of the DNA double helix (left‐hand) side) and DNA polymerases in their int