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Teratogenic phase specificity of butyl benzyl phthalate in rats

✍ Scribed by Makoto Ema; Takafumi Itami; Hironoshin Kawasaki

Book ID
103657588
Publisher
Elsevier Science
Year
1993
Tongue
English
Weight
485 KB
Volume
79
Category
Article
ISSN
0300-483X

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## Abstract Pregnant Wistar rats were given butyl benzyl phthalate (BBP) at a dose of 2.0% in the diet on days 0–20, days 0–11 or days 11–20 of pregnancy. Food consumption and body weight gain were decreased in pregnant rats given BBP. Pre‐implantation loss in the BBP‐treated groups was comparable

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The teratogenicity of butyl benzyl phthalate (BBP) was studied in Wistar rats. Pregnant rats were given BBP at a dosage of 0, 0.25, 0.5, 1.0 or 2.0% in the diet from day 0 to day 20 of pregnancy. Daily intakes of BBP were 185 mg kg-' for the 0.25% group, 375 mg kg-' for the 0.5% group, 654 mg kg-' f