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Temperature-Dependent Surface Changes in Cells Infected or Transformed by a Thermosensitive Mutant of Polyoma Virus

โœ Scribed by Walter Eckhart, Renato Dulbecco and Max M. Burger


Book ID
123649944
Publisher
National Academy of Sciences
Year
1971
Tongue
English
Weight
565 KB
Volume
68
Category
Article
ISSN
0027-8424

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๐Ÿ“œ SIMILAR VOLUMES


Temperature-dependent properties of cell
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## Abstract The properties of 121โ€6 cells were characterized. This cell line is transformed by tsโ€121, a temperatureโ€sensitive mutant of polyoma virus. Both the morphology and saturation density of the 121โ€6 cells were affected by temperature; i.e. at 39ยฐ C, the cells grew to monolayer sheets and r

Cell cycle dependence of transformation
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## Abstract Change in division capability as a phenotypic expression of cellular transformation was investigated by using one of the temperatureโ€sensitive (ts) mutants of the polyoma virusโ€transformed cell line, the 121โ€6โ€5 cells of BALB/3T3. When contact โ€inhibited cells were treated with hyaluron