Temperature-Dependent Surface Changes in Cells Infected or Transformed by a Thermosensitive Mutant of Polyoma Virus
โ Scribed by Walter Eckhart, Renato Dulbecco and Max M. Burger
- Book ID
- 123649944
- Publisher
- National Academy of Sciences
- Year
- 1971
- Tongue
- English
- Weight
- 565 KB
- Volume
- 68
- Category
- Article
- ISSN
- 0027-8424
- DOI
- 10.2307/60360
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## Abstract The properties of 121โ6 cells were characterized. This cell line is transformed by tsโ121, a temperatureโsensitive mutant of polyoma virus. Both the morphology and saturation density of the 121โ6 cells were affected by temperature; i.e. at 39ยฐ C, the cells grew to monolayer sheets and r
## Abstract Change in division capability as a phenotypic expression of cellular transformation was investigated by using one of the temperatureโsensitive (ts) mutants of the polyoma virusโtransformed cell line, the 121โ6โ5 cells of BALB/3T3. When contact โinhibited cells were treated with hyaluron