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Telomeres and Telomerase: A Simple Picture Becomes Complex

โœ Scribed by Victoria Lundblad; Woodring E Wright

Book ID
117268173
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
159 KB
Volume
87
Category
Article
ISSN
0092-8674

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Telomere shortening limits the proliferative capacity of primary human cells and restrains the regenerative capacity of organ systems during chronic diseases and aging. Telomere shortening apparently has a dual role in tumor development and progression. On the one hand, it induces chromosomal instab