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Complex roles for telomeres and telomerase in breast carcinogenesis

✍ Scribed by Steven E Artandi


Book ID
120701049
Publisher
BioMed Central
Year
2002
Tongue
English
Weight
59 KB
Volume
5
Category
Article
ISSN
1465-5411

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Telomeres and telomerase: A dual role in
✍ Ande Satyanarayana; Michael P. Manns; K. Lenhard Rudolph πŸ“‚ Article πŸ“… 2004 πŸ› John Wiley and Sons 🌐 English βš– 201 KB

Telomere shortening limits the proliferative capacity of primary human cells and restrains the regenerative capacity of organ systems during chronic diseases and aging. Telomere shortening apparently has a dual role in tumor development and progression. On the one hand, it induces chromosomal instab