Telomerase activity is involved in the maintenance of telomere length and is thought to be required for cellular immortality and oncogenesis. Three major subunits composing telomerase, human telomerase RNA (hTR), telomeraseassociated protein (TP1) and human telomerase catalytic subunit (hTERT), have
Telomerase Activation and Expression of its Catalytic Subunits in Benign and Malignant Tumors of the Parathyroid
β Scribed by Naoyoshi Onoda; Kana Ogisawa; Tetsuro Ishikawa; Chiemi Takenaka; Hideki Tahara; Masaaki Inaba; Tsutomu Takashima; Kosei Hirakawa
- Book ID
- 113047998
- Publisher
- Springer
- Year
- 2004
- Tongue
- English
- Weight
- 204 KB
- Volume
- 34
- Category
- Article
- ISSN
- 1436-2813
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract The role of DNA methylation of CpG islands in parathyroid tumorigenesis has not been analyzed in an unbiased, systematic fashion. DNA was isolated from normal and pathologic parathyroid tissues, bisulphite modified and analyzed using the Infinium HumanMethylation27 BeadChip. Distinct hi
Telomerase activity has been found in a variety of malignant tumors but only rarely in benign tumors or normal tissues. In this study, we investigated telomerase activation in 37 ovarian tumors, including benign, borderline and malignant neoplasms. Telomerase activity was detected using the telomeri