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Tauroursodeoxycholate prevents taurolithocholate-induced cholestasis and toxicity in rat liver

✍ Scribed by Schölmerich, Jürgen; Baumgartner, Ulrich; Miyai, Katsumi; Gerok, Wolfgang


Book ID
122054355
Publisher
Elsevier Science
Year
1990
Tongue
English
Weight
256 KB
Volume
10
Category
Article
ISSN
0168-8278

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Tauroursodeoxycholate and S-adenosyl-L-m
✍ Piotr Milkiewicz; Charles O. Mills; Marcelo G. Roma; Jalal Ahmed-Choudhury; Elwy 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 125 KB

The monohydroxy bile acid, taurolithocholate (TLC), causes cholestasis in vivo and in isolated perfused livers. It is also cholestatic in vitro and, in this study using isolated rat hepatocyte couplets, causes a reduction of the accumulation of (fluorescent) bile acid in the canalicular vacuoles (cV