Steroid hormones are involved in cell growth, development, and differentiation. The hormonal signal is mediated by nuclear receptors which represent a specific class of transcription factors. During the last few years, the cloning of all the major steroid hormone receptors increased our insight into
✦ LIBER ✦
Targets of activated steroid hormone receptors: basal transcription factors and receptor interacting proteins
✍ Scribed by L. Klein-Hitpass; C. Schwerk; S. Kahmann; L. Vaßen
- Publisher
- Springer
- Year
- 1998
- Tongue
- English
- Weight
- 173 KB
- Volume
- 76
- Category
- Article
- ISSN
- 0946-2716
No coin nor oath required. For personal study only.
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## Abstract Epidermal Growth Factor Receptor (EGFR) targeting in nonsmall cell lung cancer (NSCLC) is an established treatment modality; however, it only benefits a minority of patients. STAT3 (signal transducer and activator of transcription‐3) plays an important role in the oncogenic signal trans