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Effect of steroid hormones on the template activity of DNA and glucocorticoid-receptor interaction

✍ Scribed by P. P. Golikov; A. S. Bobkova

Publisher
Springer US
Year
1982
Tongue
English
Weight
376 KB
Volume
12
Category
Article
ISSN
0097-0549

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## Abstract __We analyzed the binding of five steroids to the human glucocorticoid receptor (hGR) experimentally as well as theoretically. In vitro, we measured the binding affinity of aldosterone, cortisol, estradiol, progesterone, and testosterone to hGR in competition with the ligand dexamethaso