Targeting the IL-17 Pathway in Inflammat
โ Cong-Qiu Chu
๐ Library
๐
2017
๐ Springer International Publishing, Cham
๐ English
โฆ LIBER โฆ
๐
Targeting the IL-17 Pathway in Inflammatory Disorders
โ Scribed by Cong-Qiu Chu (auth.)
- Publisher
- ADIS
- Year
- 2017
- Tongue
- English
- Leaves
- 112
- Edition
- 1
- Category
- Library
โฌ Acquire This Volume
No coin nor oath required. For personal study only.
โฆ Synopsis
This book provides an overview of the discovery and structure of IL-17, including its pathogenesis and role in chronic inflammation and autoimmunity. To capture the latest developments and product approvals the book also discusses the therapeutic advances and looks at emerging therapies targeting the IL-17 pathway. IL-17 is a pro-inflammatory cytokine that has a key role in inflammation, autoimmunity, and host defense in a number of inflammatory disorders such as rheumatoid arthritis, psoriatic arthritis and psoriasis, ankylosing spondylitis, multiple sclerosis, and inflammatory bowel disease. The discovery of the IL-17-Th17 pathway has seen exciting development in the field of immunology and inflammation research, which has led to a number of recent regulatory approvals.
โฆ Table of Contents
Front Matter....Pages i-xv
Overview of IL-17 Family....Pages 1-9
IL-17 in Host Defense....Pages 11-28
Th17 Cells: Differentiation and Regulation....Pages 29-46
The Role of IL-17/Th17 Pathway in the Pathogenesis of Autoimmune Inflammatory Diseases....Pages 47-53
Therapeutic Applications: Strategies and Molecules Targeting the IL-17/Th17 Pathway....Pages 55-99
Concluding Remarks....Pages 101-102
โฆ Subjects
Rheumatology;Dermatology;Pharmacotherapy;Primary Care Medicine;Public Health
๐ SIMILAR VOLUMES
Targeting the Wnt Pathway in Cancer
โ Paul Polakis (auth.), Kathleen H. Goss, Michael Kahn (eds.)
๐ Library
๐
2011
๐ Springer-Verlag New York
๐ English
<p>The Wnt pathway is an evolutionarily conserved signaling network that is critical for mammalian development and adult tissue maintenance, and, importantly, hyperactivated in most human cancers. Almost two decades of study has confirmed that Wnt signaling is necessary and sufficient for cancer pat
Targeting the Wnt Pathway in Cancer
โ Paul Polakis (auth.), Kathleen H. Goss, Michael Kahn (eds.)
๐ Library
๐
2011
๐ Springer-Verlag New York
๐ English
<p>The Wnt pathway is an evolutionarily conserved signaling network that is critical for mammalian development and adult tissue maintenance, and, importantly, hyperactivated in most human cancers. Almost two decades of study has confirmed that Wnt signaling is necessary and sufficient for cancer pat
Targeting Epigenetics in Inflammatory Lu
โ Gaurav Gupta (editor), Brian G. Oliver (editor), Kamal Dua (editor), Md Khadem A
๐ Library
๐
2023
๐ Springer
๐ English
<p><span>This book discusses the role of epigenetics in pathogenesis of different pulmonary diseases, including chronic obstructive pulmonary disease, lung cancer, pulmonary tuberculosis, idiopathic pulmonary fibrosis and pulmonary infections. It also explores post-translational modifications in DNA
Inflammatory Disorders
โ Mieczyslaw Pokorski (eds.)
๐ Library
๐
2015
๐ Springer International Publishing
๐ English
<p>The mechanistic basis of chronic inflammation remains unclear. The research sheds new light on the immune cells expressing the activation markers HLA-DR and regulatory T cells (Tregs) and the cells expressing Siglec receptors as being key players in the immune system responsiveness to antigens an
Inflammatory Pathways in Diabetes: Bioma
โ Michael Pugia (eds.)
๐ Library
๐
2015
๐ Springer International Publishing
๐ English
<p><p>This book discusses recent advances in new anti- and pro-inflammatory pathways in diabetic disease, and identifies new diagnostic immunological methods that offer potential companion diagnostics for diabetic diseases. New methods in proteomics, mass spectroscopy, immunological assay design, me