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Targeting of host-cell ubiquitin and ubiquitin-like pathways by bacterial factors

✍ Scribed by Boyer, Laurent; Lemichez, Emmanuel


Book ID
109959857
Publisher
Nature Publishing Group
Year
2004
Tongue
English
Weight
511 KB
Volume
2
Category
Article
ISSN
1740-1526

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## Abstract Insulin‐like growth factor‐I receptor (IGF‐IR) is often overexpressed in malignant tumors, and is involved in the establishment and maintenance of malignant phenotypes. Tyrosine kinase receptor endocytosis is commonly triggered by ligand binding and occurs via clathrin‐coated vescicles