𝔖 Bobbio Scriptorium
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Targeting Chronic Myeloid Leukemia Stem Cells

✍ Scribed by G. Vignir Helgason; Graham A. R. Young; Tessa L. Holyoake


Book ID
107540266
Publisher
Current Science Inc.
Year
2010
Tongue
English
Weight
221 KB
Volume
5
Category
Article
ISSN
1558-8211

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## Abstract Chronic Myeloid Leukemia (CML), a myeloproliferative disease of stem cell origin, is characterized by the presence of the Philadelphia (Ph) chromosome and the __bcr‐abl__ oncogene. The BCR‐ABL fusion gene product, thought to be causative in CML, has multiple effects on diverse cell func