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Targeted expression of MYCN causes neuroblastoma in transgenic mice

โœ Scribed by Weiss, W. A.


Book ID
111744785
Publisher
Nature Publishing Group
Year
1997
Tongue
English
Weight
727 KB
Volume
16
Category
Article
ISSN
0261-4189

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To develop specific conditional gene ablation in the hematopoietic myeloid-osteoclast lineage, transgenic mice expressing Cre recombinase under the control of the CD11b promotor were generated on the C57BL/6 background. The cellular specificity of Cre activity following recombination was quantified