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Targeted epidermal growth factor receptor nanoparticle bioconjugates for breast cancer therapy

✍ Scribed by Sarbari Acharya; Fahima Dilnawaz; Sanjeeb K. Sahoo

Book ID
108070051
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
985 KB
Volume
30
Category
Article
ISSN
0142-9612

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Recent studies demonstrated that tumors overexpressing the epidermal growth factor receptor (EGF-R, erbB-1) are associated with poor clinical outcome. This led to the development of a variety of monoclonal antibodies targeting the extracellular domain of this receptor tyrosine kinase. The aim of our