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Targeted Delivery of GDNF Through the Blood-Brain Barrier by Mri-Guided Focused Ultrasound

✍ Scribed by Feng, W.; Yu, S.; Lin, L.; Li, L.; Youli, C.; Hairong, Z.; Xin, L.; Fei, Y.; Chao, Z.; Chengyu, S.; Jie, S.; Shukun, L.; Yun, C.


Book ID
123086132
Publisher
Elsevier Science
Year
2013
Tongue
English
Weight
42 KB
Volume
39
Category
Article
ISSN
0301-5629

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## Abstract The clinical application of chemotherapy to brain tumors has been severely limited because antitumor agents are typically unable to penetrate an intact blood‐brain barrier (BBB). Although doxorubicin (DOX) has been named as a strong candidate for chemotherapy of the central nervous syst