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Targeted cytotoxic analog of luteinizing hormone–releasing hormone AN-207 inhibits growth of OV-1063 human epithelial ovarian cancers in nude mice

✍ Scribed by Masahiro Miyazaki; Andrew V. Schally; Attila Nagy; Najib Lamharzi; Gabor Halmos; Karoly Szepeshazi; Patricia Armatis


Book ID
113986548
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
205 KB
Volume
180
Category
Article
ISSN
1097-6868

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Targeted cytotoxic analog of luteinizing
✍ Kopp�n, Miklos; Nagy, Attila; Schally, Andrew V.; Plonowski, Artur; Halmos, G�bo 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 238 KB 👁 2 views

## Background: Receptors for luteinizing hormone-releasing hormone (lh-rh) found in prostate cancers might be used for targeting of chemotherapeutic agents. doxorubicin derivative 2-pyrrolinodoxorubicin (an-201) can be linked to carrier analog [d-lys6]lh-rh to form the targeted cytotoxic analog of