✦ LIBER ✦

Target discovery: Blocking BTK in B-cell disorders

✍ Scribed by Flemming, Alexandra

Book ID: 109951196
Publisher: Nature Publishing Group
Year: 2010
Tongue: English
Weight: 214 KB
Volume: 9
Category: Article
ISSN: 1474-1776
DOI: 10.1038/nrd3262

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Btk function in B cell development and r

Btk function in B cell development and response

✍ Anne B Satterthwaite; Zuomei Li; Owen N Witte 📂 Article 📅 1998 🏛 Elsevier Science 🌐 English ⚖ 97 KB

Role of Btk in B cell development and si

Role of Btk in B cell development and signaling

✍ Stephen Desiderio 📂 Article 📅 1997 🏛 Elsevier Science 🌐 English ⚖ 669 KB

Bruton's tyrosine kinase (Btk), the target of inactivating mutations in X-linked immunodeficiency diseases of mice and humans, is essential for normal B cell responsiveness. Recent studies have outlined a mechanism for the activation of Btk by B cell receptor engagement and have identified proximal

Interaction of Btk and Akt in B cell sig

Interaction of Btk and Akt in B cell signaling

✍ Jessica Lindvall; Tahmina C Islam 📂 Article 📅 2002 🏛 Elsevier Science 🌐 English ⚖ 291 KB

Specific Inhibition of BTK Is Effective

Specific Inhibition of BTK Is Effective in B-Cell Malignancies

📂 Article 📅 2012 🏛 American Association for Cancer Research 🌐 English ⚖ 393 KB

B cells as therapeutic targets in autoim

B cells as therapeutic targets in autoimmune neurological disorders

✍ Dalakas, Marinos C 📂 Article 📅 2008 🏛 Nature Publishing Group 🌐 English ⚖ 756 KB

Correction of B-cell development in Btk-

Correction of B-cell development in Btk-deficient mice using lentiviral vectors with codon-optimized human BTK

✍ Ng, Y Y; Baert, M R M; Pike-Overzet, K; Rodijk, M; Brugman, M H; Schambach, A; B 📂 Article 📅 2010 🏛 Nature Publishing Group 🌐 English ⚖ 962 KB