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Tandem radical cyclisations leading to indolizidinones and pyrrolizidinones

✍ Scribed by S. Richard Baker; Andrew F. Parsons; Jean-François Pons; Michelle Wilson

Publisher
Elsevier Science
Year
1998
Tongue
French
Weight
238 KB
Volume
39
Category
Article
ISSN
0040-4039

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✦ Synopsis

Reaction of various dehydroamino esters with tin hydrides resulted in 5-endo-5-exo or 5-endo-6endo tandem cyclisafion reactions. The preferred pathway was dependent on alkene substitution and the bicyclic products have potential application in indolizidine and pyrrolizidine alkaloid synthesis.

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