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T2-shortening by strongly magnetized spheres: A chemical exchange model

โœ Scribed by Rodney A. Brooks


Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
87 KB
Volume
47
Category
Article
ISSN
0740-3194

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โœฆ Synopsis


Abstract

It is shown that a chemical exchange model can reproduce nuclear magnetic relaxation caused by diffusion of water molecules near strongly magnetized particles. The agreement is based on the similarity (but not equivalence) of the respective โ€œvisitโ€limitingโ€ mechanisms in the echoโ€limited regime. The model leads to a single equation that predicts relaxation behavior in both the motionalโ€averaging and visitโ€limited regimes. When combined with the staticโ€dephasing regime equation, the result is a simple theory (for spheres) that covers the entire range of diffusion times. Magn Reson Med 47:388โ€“391, 2002. Published 2002 Wileyโ€Liss, Inc.


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Chemical exchange (CE) theory is compared with two theories of T2-shortening caused by microscopic magnetic centers: inner- and outer-sphere relaxation theory (long-echo limit) and mean gradient diffusion theory (short-echo limit). The CE equation is shown to be identical to these theories in the re