## Abstract It is shown that a chemical exchange model can reproduce nuclear magnetic relaxation caused by diffusion of water molecules near strongly magnetized particles. The agreement is based on the similarity (but not equivalence) of the respective “visit‐limiting” mechanisms in the echo‐limite
On T2-shortening by strongly magnetized spheres: A partial refocusing model
✍ Scribed by Pierre Gillis; Francis Moiny; Rodney A. Brooks
- Publisher
- John Wiley and Sons
- Year
- 2002
- Tongue
- English
- Weight
- 138 KB
- Volume
- 47
- Category
- Article
- ISSN
- 0740-3194
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✦ Synopsis
Abstract
Computer simulations of water transverse relaxation induced by superparamagnetic particles are shown to disagree with the available theories, covering the slow diffusion domain. Understanding these new simulations, not in the slow diffusion domain, thus requires a new theoretical approach. A “partial refocusing model” is introduced for this purpose; it is based on a spatial division between an inner region where the gradients are too strong for the refocusing pulses to be efficient and an outer region where they are efficient. This model agrees with published simulations of relaxation induced by magnetic dipoles approximated as points. The validity domains of the various models are also compared. Magn Reson Med 47:257–263, 2002. © 2002 Wiley‐Liss, Inc.
📜 SIMILAR VOLUMES
Chemical exchange (CE) theory is compared with two theories of T2-shortening caused by microscopic magnetic centers: inner- and outer-sphere relaxation theory (long-echo limit) and mean gradient diffusion theory (short-echo limit). The CE equation is shown to be identical to these theories in the re