T lymphocyte differentiation in vitro in ataxia telangiectasia associated with lymphosarcoma
β Scribed by L. Boumsell; G.S. Incefy; A. Bernard; S. Schwartz; E. Smithwick; R.A. Good
- Book ID
- 118538751
- Publisher
- Elsevier Science
- Year
- 1975
- Tongue
- English
- Weight
- 291 KB
- Volume
- 87
- Category
- Article
- ISSN
- 1097-6833
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Ataxia telangiectasia (A-T) is an autosomal recessive disorder in which patients show an unusual predisposition to malignant disease, including T-cell chronic lymphocytic leukaemia. We report here the steady growth over 5 years of a complex, cytogenetically abnormal clone of T lymphocytes in an A-T
## Abstract Ataxia telangiectasia (AT) is a human autosomal recessive disorder in which patients show a marked predisposition to malignant disease and cytogenetic abnormalities. We report here the levels of spontaneously occurring chromosome aberrations and particularly the presence of cytogenetica