T cells in multiple sclerosis and experimental autoimmune encephalomyelitis
β Scribed by J. M. Fletcher; S. J. Lalor; C. M. Sweeney; N. Tubridy; K. H. G. Mills
- Book ID
- 108701206
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 529 KB
- Volume
- 162
- Category
- Article
- ISSN
- 0009-9104
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n experimental allergic encephalomyelitis (EAE), an animal model for multiple sclerosis (MS), T helper 1 (Th1)/Th2 immunological effector pathways are altered. Neuropathological findings and results from MS treatment trials suggest that our view of MS and other putative autoimmune diseases and their
## Abstract Triptolide (TPT), a diterpenoid triepoxide, is the major component isolated from the Chinese herb __Tripterygium wilfordii__ Hook. f. Previous studies have shown that TPT has immunosuppressive properties and is effective in prolonging graft survival and suppressing autoimmune responses.